This drug is used to treat high blood pressure (hypertension).
Avalide tablets contain a combination of hydrochlorothiazide and irbesartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Irbesartan is an angiotensin II receptor antagonist. Irbesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
The dosage is based on your medical condition and response to treatment. Take this medication by mouth as directed by your doctor, usually once daily with or without food. If this medication causes you to urinate more frequently, it is best to take it at least 4 hours before your bedtime to prevent having to get up to urinate.
You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated.
You need to avoid taking Avalide with aliskiren if you have kidney disease. To make sure this medicine is safe for you, tell your doctor if you have ever had liver disease; congestive heart failure; glaucoma; low or high levels of potassium in your blood; asthma or allergies; high cholesterol or triglyceride levels; gout; lupus; diabetes; or an allergy to penicillin. Do not use if you are pregnant. If you become pregnant, stop taking this medicine. Limit alcoholic beverages as drinking alcohol can further lower your blood pressure and may cause side effects.
Possible side effect
The most common side effects are muscle or joint pain, dizziness or feeling tired. Call your doctor at once if you have eye pain, vision problems; a light-headed feeling, like you might pass out; little or no urinating; jaundice (yellowing of the skin or eyes); easy bruising, unusual bleeding; or signs of an electrolyte imbalance (increased thirst or urination, leg cramps, constipation, vomiting, irregular heartbeats, fluttering in your chest, numbness or tingling, muscle weakness). In rare cases, Avalide can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever.
Do not use potassium supplements or salt substitutes while you are taking Avalide, unless your doctor has told you to. If you also take cholestyramine or colestipol, avoid taking these medications within 4 hours before or 4 hours after you take Avalide. Do not take Avalide if you taking any of the following medication: carbamazepine; lithium; insulin or oral diabetes medicine; or NSAIDs (nonsteroidal anti-inflammatory drugs), such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include fast or slow heartbeat, feeling light-headed, or fainting.
Store the medicine at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.
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